Greetings! The connection could be possible! Most of my family originally hailed from the region. There were so many Wells families roaming around that region and as of this time soem had no direct connections that I have heard of, yet. But they also intermarried along the line, there were so many people to choose from in thsoe days you know, so blood lines did mingle.
You ought to contact Orin Wells at the Wells Family Research Association web site, he may be able to recognize the family or know someone who could, the url is - http://www.rootsweb.com/~wellsfam/wfrahome.html
there are links there as well to other Wells Families.
Do you know anything frurther back than your grandfather or Great Grandfather? My line is from Ol' Zacharaih Wells who m. Abigail Osborne. The line goes something like this, if I can remember it correctly when you hit 50 things to to get lost, Ol' Zack to Jeremiah to James franklin to Winfield to Emerson Galington to Guy Galington to Claude Emerson Wells. My grandfather moved the family out of VA becasue he didn;t want his boys growing up in the Coal mines. My grandmother was from the Robinette family, Sarah Catherine d/o of "Uncle Billy" William Robinette a primitive baptist minister. And some of teh other families I am allied to through marriage are Culbertson, Fugate, Compton and going further back there are the Tates, Woods, etc. I have my family reports posted at the Family Tree Maker web site users pages. The url for them is http://www.familytreemaker.com/users/w/e/l/Claude-E-Wells/
have a look and enjoy. Good Luck with your search and if I can help please contact me on firstname.lastname@example.org